Opportunity Information: Apply for RFA ES 23 012
The Undergraduate Research Education Program (UP) to Enhance Diversity in the Environmental Health Sciences (R25 Clinical Trial Not Allowed), funding opportunity number RFA-ES-23-012, is a National Institutes of Health (NIH) grant led by the National Institute of Environmental Health Sciences (NIEHS). It sits in the environment and health funding category (CFDA 93.113) and uses the NIH R25 Research Education Grant mechanism, which is designed to support structured educational and training activities rather than to fund a traditional research project. The central purpose of this program is to strengthen and diversify the pipeline of future researchers in environmental health sciences by supporting educational activities that broaden participation in biomedical, behavioral, and clinical research careers connected to environmental health.
A defining feature of this opportunity is its emphasis on hands-on research experiences for undergraduate students, specifically those at the junior and senior level. The FOA encourages creative program designs that give students meaningful exposure to environmental health research, typically through mentored research experiences, skill-building activities, and structured educational supports that help participants build research confidence, competence, and a clearer pathway into graduate school, professional school, or research-focused careers. Because the overarching goal is workforce diversification, proposed activities are expected to be intentionally designed to recruit, support, and retain students from groups that are underrepresented in the environmental health sciences research enterprise and to reduce barriers that can limit persistence in research training.
The “Clinical Trial Not Allowed” designation means applicants must not propose clinical trials under this award. In practical terms, the program can include training and education related to human health and environmental exposures, but the supported activities cannot include a study that meets NIH’s definition of a clinical trial (for example, prospective assignment of human participants to an intervention to evaluate effects on health-related outcomes). This matters for program planning because it shapes what kinds of research experiences can be offered to students and what kinds of projects mentors can host under the program’s umbrella.
Eligibility is broad and includes many types of U.S.-based institutions and organizations. Eligible applicants listed include state, county, city or township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations that are not federally recognized tribal governments; public housing authorities/Indian housing authorities; nonprofits with and without 501(c)(3) status (other than institutions of higher education); for-profit organizations other than small businesses; and small businesses. The FOA also calls out additional eligible applicant types that align strongly with the diversity-focused mission, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions. At the same time, it clearly restricts foreign involvement: non-U.S. entities are not eligible to apply, non-U.S. components of U.S. organizations are not eligible to apply, and foreign components as defined by the NIH Grants Policy Statement are not allowed.
The opportunity was created on 2023-12-07 and had an original closing date of 2024-02-14. The listed award ceiling is $125,000, indicating an upper limit on the amount that may be awarded under this FOA (typically interpreted as a cap on direct costs per year or a similar budgeting boundary depending on the FOA specifics). While the record notes “ExpectedAwards:” without a number provided, the ceiling and the R25 structure suggest awards are intended to support program staff effort, student research experiences, training-related costs, and other allowable educational program expenses rather than large-scale laboratory infrastructure or major research operations.
In short, this NIEHS R25 program is aimed at building well-designed undergraduate research education experiences in environmental health sciences, with a strong, explicit commitment to enhancing diversity in the research workforce. Competitive projects under this FOA would be expected to show thoughtful recruitment and mentoring plans, structured research experiences for juniors and seniors, and clear educational activities that help students gain the skills, networks, and preparation needed to continue toward research careers in environmental health, while staying within the non-clinical-trial boundary and the U.S.-only eligibility requirements.Apply for RFA ES 23 012
- The National Institutes of Health in the environment, health sector is offering a public funding opportunity titled "Undergraduate Research Education Program (UP) to Enhance Diversity in the Environmental Health Sciences (R25 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113.
- This funding opportunity was created on 2023-12-07.
- Applicants must submit their applications by 2024-02-14. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $125,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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| Funding Opportunity |
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| Hazardous Materials Worker Health and Safety Training (U45 Clinical Trials Not Allowed) Apply for RFA ES 24 001 Funding Number: RFA ES 24 001 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
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| CCRP Initiative: Chemical Threat Agent-induced Pulmonary and Ocular Pathophysiological Mechanisms (R01 Clinical Trial Not Allowed) Apply for RFA ES 24 005 Funding Number: RFA ES 24 005 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Revolutionizing Innovative, Visionary Environmental Health Research (RIVER) (R35 Clinical Trial Optional) Apply for RFA ES 24 004 Funding Number: RFA ES 24 004 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Epitranscriptomics Crosstalks and Toxicants (EPCOT) (R01 Clinical Trials Not Allowed) Apply for RFA ES 25 001 Funding Number: RFA ES 25 001 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $500,000 |
| Environmental Health Sciences Core Centers Program (P30 Clinical Trials Optional) Apply for RFA ES 25 002 Funding Number: RFA ES 25 002 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| NIH Blueprint for Neuroscience: Coordination Center for Interoception Research (BPCCIR) (U24, Clinical Trial Not Allowed) Apply for RFA AT 25 004 Funding Number: RFA AT 25 004 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
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