Opportunity Information: Apply for CDC RFA GH15 16270301SUPP18

The grant opportunity "Protecting and Improving Public Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity, and Security" (CDC RFA GH15 16270301SUPP18) is a CDC cooperative agreement designed to help countries strengthen their ability to handle major public health threats, with a strong emphasis on advancing the Global Health Security Agenda (GHSA). The central idea is to support practical, on-the-ground work that protects health globally by improving how countries prevent, detect, and respond to infectious disease outbreaks and other serious health threats. A key feature is that projects are expected to be carried out through close partnership with national Ministries of Health (MoH), reinforcing country ownership and alignment with national priorities rather than operating in parallel systems.

A major driver of this NOFO is urgent outbreak response capacity, especially in the context of Ebola and other fast-moving infectious disease events, including Public Health Emergencies of International Concern (PHEICs). Funding is meant to support immediate and near-term response actions while also building longer-term systems so countries are better prepared before the next emergency hits. In practice, that means applicants are expected to propose activities that help countries stop outbreaks earlier, identify them faster, and respond more effectively once cases appear. The opportunity also explicitly highlights strengthening border health and security measures, recognizing that outbreaks often spread through travel and trade routes and that cross-border coordination and screening can be critical to containing threats.

The NOFO is framed around GHSA targets and action packages, so proposed work should map clearly to those internationally recognized capacity areas. Rather than building entirely new structures, applicants are encouraged to build on existing public health infrastructure and focus on priorities that are mutually agreed upon with the host country. The intent is to strengthen regional and national partnerships, expand public health leadership and workforce capability, improve strategic collaboration across sectors, and promote integrated health programming implemented through or in strong collaboration with MoH systems. In other words, the CDC is looking for proposals that reinforce the core functions of public health and improve how different parts of the health system work together during routine operations and during emergencies.

Another required element is performance monitoring and evaluation. Applicants must plan for how they will track overall program performance and measure progress of the specific projects or activities they implement, including progress toward GHSA target achievement. This implies that proposals should include practical indicators, reporting approaches, and ways to use data for course correction during implementation, not just end-of-project evaluation. Because this is a cooperative agreement, recipients should also expect substantial CDC involvement and collaboration during implementation, which typically includes joint planning, technical support, and shared accountability for results.

In terms of funding mechanics, this is a discretionary cooperative agreement under the Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), with the activity category listed as Health and CFDA number 93.318. The award ceiling is $2,000,000, and CDC anticipated making about three awards under this specific posting. The opportunity was created June 29, 2018, with an original closing date of July 28, 2018, and electronically submitted applications were due by 11:59 p.m. Eastern Time on the due date.

Eligibility is listed broadly as "Others," with additional eligibility details referenced in the full NOFO. A notable restriction is that applicants who were awarded under CDC-RFA-GH14-1418 for similar activities cannot apply for the same scope again. However, prior awardees may apply if they are proposing to expand into activities that were not included in the earlier award but are included under this announcement. The NOFO also notes that special consideration may be given to projects involving countries identified as GHSA Phase One countries in the NOFO's funding strategy section, signaling a preference for early GHSA partner countries where rapid progress toward core capacities was a priority.

Overall, the opportunity is aimed at strengthening national and regional public health security by combining urgent outbreak response support with sustained systems-building. The most competitive proposals under this type of NOFO would typically show strong MoH partnership and alignment with country plans, a clear connection to GHSA targets, realistic and measurable implementation steps, and a solid monitoring and evaluation approach that demonstrates how progress and impact will be tracked over time.

  • The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Protecting and Improving Public Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity, and Security" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.318.
  • This funding opportunity was created on Jun 29, 2018.
  • Applicants must submit their applications by Jul 28, 2018 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $2,000,000.00 in funding.
  • The number of recipients for this funding is limited to 3 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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