Opportunity Information: Apply for RFA MH 20 145
The BRAIN Initiative funding opportunity "Marmoset Colonies for Neuroscience Research (U24 Clinical Trials Not Allowed)" (RFA-MH-20-145) is a National Institutes of Health (NIH) cooperative agreement designed to expand access to the common marmoset as a research model for neuroscience. The central idea behind the program is that marmosets are increasingly valuable for studying the primate brain because many aspects of their behavior and neurobiology are closer to humans than traditional rodent models, and because recent advances now make germline transmission of introduced genetic material feasible in this species. Even with growing demand, the existing academic colonies and commercial suppliers are not able to produce enough animals to meet the needs of the neuroscience community, which creates a major bottleneck for BRAIN Initiative-aligned research that depends on reliable access to marmosets.
The mechanism is a U24 cooperative agreement, meaning recipients should expect substantial scientific and/or programmatic involvement from NIH compared with a standard research grant. In practice, this type of award is commonly used to support shared research infrastructure and community-serving resources rather than a single-lab research project. The "Clinical Trials Not Allowed" designation indicates that applications should not propose clinical trials; the emphasis is on establishing, expanding, or operating marmoset colony capacity and associated resource functions that enable neuroscience research rather than testing clinical interventions.
Eligibility is broad and includes many U.S.-based organization types across government, academia, nonprofit, and industry. Eligible applicants include state, county, city/township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized; public housing authorities/Indian housing authorities; nonprofits with and without 501(c)(3) status (other than institutions of higher education); for-profit organizations other than small businesses; and small businesses. The notice also explicitly highlights additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), eligible federal agencies, faith-based or community-based organizations, regional organizations, and U.S. territories or possessions.
Foreign participation is limited in a way that is common for NIH opportunities focused on building U.S. research capacity. Non-domestic (non-U.S.) entities (foreign organizations/institutions) are not eligible to apply, and non-domestic components of U.S. organizations are also not eligible to apply as components. At the same time, "foreign components" as defined in the NIH Grants Policy Statement are allowed, which generally means a U.S. applicant may include certain well-justified, discrete project elements performed outside the United States when they are necessary for the project and meet NIH policy requirements.
The opportunity sits within NIH's broader portfolio supporting neuroscience and mental health-related research infrastructure, reflected in the multiple CFDA numbers listed (93.113, 93.121, 93.173, 93.213, 93.242, 93.273, 93.279, 93.286, 93.853, 93.865, 93.866, 93.867). The opportunity was created on June 25, 2019, and the original closing date was October 3, 2019. The public listing does not specify an award ceiling or the expected number of awards, suggesting those details were either provided in the full solicitation text or were to be determined based on appropriations and application quality.
Overall, the grant is aimed at solving a practical capacity problem: ensuring the neuroscience community can obtain enough marmosets to conduct cutting-edge primate brain research, including work that may benefit from genetically modified lines. Applicants are expected to propose a program that materially increases availability and reliability of marmoset resources for research, consistent with NIH oversight under a cooperative agreement and without proposing clinical trial activities.Apply for RFA MH 20 145
- The National Institutes of Health in the education, environment, health, income security and social services sector is offering a public funding opportunity titled "BRAIN Initiative: Marmoset Colonies for Neuroscience Research (U24 Clinical Trials Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.173, 93.213, 93.242, 93.273, 93.279, 93.286, 93.853, 93.865, 93.866, 93.867.
- This funding opportunity was created on 2019-06-25.
- Applicants must submit their applications by 2019-10-03. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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| Funding Opportunity |
|---|
| NIH Blueprint for Neuroscience Research Education Program on Translational Devices (R25 Clinical Trial Not Allowed) Apply for RFA NS 20 003 Funding Number: RFA NS 20 003 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $250,000 |
| NIH Blueprint Program for Enhancing Neuroscience Diversity through Undergraduate Research Education Experiences (BP-ENDURE) (R25 Clinical Trial Not Allowed) Apply for RFA NS 20 015 Funding Number: RFA NS 20 015 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Clinical Trial Readiness (R21 Clinical Trial Not Allowed) Apply for RFA OD 20 004 Funding Number: RFA OD 20 004 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $200,000 |
| Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32) Apply for PA 20 142 Funding Number: PA 20 142 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Research Project Grant (Parent R01 Basic Experimental Studies with Humans Required) Apply for PA 20 184 Funding Number: PA 20 184 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Pathway to Independence Award (Parent K99/R00 Independent Basic Experimental Studies with Humans Required) Apply for PA 20 189 Funding Number: PA 20 189 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Quantitative Research Development Award (Parent K25 Independent Basic Experimental Studies with Humans Required) Apply for PA 20 198 Funding Number: PA 20 198 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Basic Experimental Studies with Humans Required) Apply for PA 20 204 Funding Number: PA 20 204 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Basic Experimental Studies with Humans Required) Apply for PA 20 201 Funding Number: PA 20 201 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Required) Apply for PA 20 202 Funding Number: PA 20 202 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Emergency Awards: RADx-UP Coordination and Data Collection Center (CDCC) (U24 Clinical Trial Optional) Apply for RFA OD 20 013 Funding Number: RFA OD 20 013 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Tools for Germline Gene Editing in Marmosets (U01 - Clinical Trial Not Allowed) Apply for RFA DA 21 006 Funding Number: RFA DA 21 006 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Fertility Status as a Marker for Overall Health (R01 Clinical Trial Optional) Apply for PAR 20 281 Funding Number: PAR 20 281 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Fertility Status as a Marker for Overall Health (R21 Clinical Trial Not Allowed) Apply for PAR 20 282 Funding Number: PAR 20 282 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Centers to Advance Research in Endometriosis (CARE) (P01 Clinical Trial Not Allowed) Apply for RFA HD 21 002 Funding Number: RFA HD 21 002 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $1,000,000 |
| NIH Blueprint for Neuroscience Research: Functional Neural Circuits of Interoception (R01, Clinical Trial Not Allowed) Apply for RFA AT 21 003 Funding Number: RFA AT 21 003 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $375,000 |
| Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Humans Required) Apply for PAR 21 039 Funding Number: PAR 21 039 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Blueprint for Neuroscience Research: Tools and Technologies to Explore Nervous System Biomolecular Condensates (R21 Clinical Trial Not Allowed) Apply for RFA DA 22 008 Funding Number: RFA DA 22 008 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $200,000 |
| Building Interdisciplinary Research Careers in Women's Health Program (BIRCWH) (K12 Clinical Trial Optional) Apply for RFA OD 21 006 Funding Number: RFA OD 21 006 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $600,000 |
| NIH Blueprint and BRAIN Initiative Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award (F99/K00 Clinical Trial Not Allowed) Apply for RFA NS 21 012 Funding Number: RFA NS 21 012 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
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